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Research Assistant - Chiang Ying-Chih Project, Kobilka Institute of Innovative Drug Discovery (Ref.PR2025/068/01)

Deadline: Jun 30,2025 Research fellow

研究院介绍

科比尔卡创新药物开发研究院(KIIDD)是香港中文大学(深圳)组建的首批诺贝尔奖科学家实验室之一。在研究院学术带头人布莱恩·科比尔卡教授(Prof. Brian K. Kobilka)的牵头下,KIIDD也成了大学建设成为全球一流的研究型大学的重要里程碑。研究院的重点研究领域集中在新药开发上,研究方向主要包括药物受体结构生物学研究、药物计算化学研究、功能药物分子的有机合成和药物化学的研究、受体功能药物分子的功能药理学等。通过X射线单晶衍射、核磁共振和电子显微学等方法进行药物受体结构生物学研究,借助计算机辅助和分子模拟进行药物设计,对功能药物分子合成和药物化学、药理学原理进行研究,进行对新型药物进行合成制备,为今后的临床研究提供药理学理论支撑。研究院秉承立项任务书的目标,继续利用前沿技术开展药物靶点基础转化研究,并鼓励探索和创新,为后期临床研究提供药理支撑和源头创新,产出高水平研究成果并期望与顶级制药公司合作,以实现创新药物商业化。

 

团队介绍

江瑛芝教授课题组使用计算生物学手段研究药物与靶点之间的相互作用,应用于多种课题,包括GPCR与其它膜蛋白的小分子药物筛选和药物设计、微生物的耐药性机制解析等。

课题组拟招募3-5名研究助理从事以下研究:

1. 使用量子力学计算开发高精度的药物分子力场参数,并改良现有软件;

2. 使用虚拟筛选与自由能计算进行计算机辅助药物设计;

3. 使用大数据与深度学习方法设计全新抗菌肽。

 

应聘条件

1. 物理或化学相关专业应届硕士;

2. 有计算相关研究经验或具备计算机专业背景知识;

3. 具备良好的中英文写作能力;

4. 有文章发表经验。

 

福利待遇

根据中国现行的劳动法所规定薪酬与相关福利,薪资详情可面议。

 

申请方式

请将完整的中、英文简历,并附上两位推荐人的姓名及联系方式,发送至邮箱:chiangyc@cuhk.edu.cn。本职位有效日期至合适人选到岗之日为止。

 

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